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Image Search Results
Journal: Translational Psychiatry
Article Title: Cocaine induces differential circular RNA expression in striatum
doi: 10.1038/s41398-019-0527-1
Figure Lengend Snippet: a The Scatter-Plot is used to analyze the variation of circRNA expression between samples or groups. The values of X- and Y -axis in the Scatter-Plot are normalized (log2 scaled). The green lines represent fold change lines. CircRNAs above the top green line and below the bottom green line indicate more than 2.0 fold change of circRNAs between cocaine group and saline group. b Volcano plot indicates the fold change (two-fold up and down), respectively [Log2 (fold change), x -axis] and p = 0.05 [Log10 ( p value), y -axis] for circRNAs. The red point in the plot represents the differentially expressed circRNA with statistical significance. c Considering the fold change and p -values, 18 circRNAs were up-regulated and 72 were down-regulated. d The distribution of differentially expressed circRNAs in chromosomes
Article Snippet: Limited circRNA probes may attribute to this phenomenon because Arraystar
Techniques: Expressing
Journal: Translational Psychiatry
Article Title: Cocaine induces differential circular RNA expression in striatum
doi: 10.1038/s41398-019-0527-1
Figure Lengend Snippet: a The network consists of down-regulated circRNAs (blue nodes) and their target miRNAs (orange nodes). b The network contains up-regulated circRNAs (red nodes) and their target miRNAs (green nodes). c A magnified network of mmu_circRNA_002381, mmu_circRNA_013587, mmu_circRNA_003834 and mmu_circRNA_002520 and their target miRNAs is presented. d The detailed annotation for mmu-miR-138-5p/mmu_circRNA_002381 interaction
Article Snippet: Limited circRNA probes may attribute to this phenomenon because Arraystar
Techniques:
Journal: Translational Psychiatry
Article Title: Cocaine induces differential circular RNA expression in striatum
doi: 10.1038/s41398-019-0527-1
Figure Lengend Snippet: a Cocaine self-administration induces mmu_circRNA_002381 and mmu_circRNA_003834 up-regulation, while mmu_circRNA_002520 was down-regulated. b Cocaine hyperlocomotor behavior induces the same modification as those in mmu_circRNA_002381, mmu_circRNA_002520 and mmu_circRNA_003834. c The expression level of mmu_circRNA_002381 was detected after si-mmu_circRNA_002381 treatment in N2a cells. d , e The mRNA and protein expressions of neuroplasticity genes, such as limk1, bdnf, sirt1 , and creb1 were detected following knockdown of mmu_circRNA_002381 using si-mmu_circRNA_002381. f Detailed annotation for mmu-miR-138-5p/mmu_circRNA_003834 interaction is displayed. * P < 0.05, ** P < 0.01, *** P < 0.001
Article Snippet: Limited circRNA probes may attribute to this phenomenon because Arraystar
Techniques: Modification, Expressing